The Structure and Prevalence of Major Risk Factors of Osteoporosis in Uzbek Women over 50

Background: Osteoporosis is a systemic metabolic disease of skeleton, characterized by decrease of bone mass and impaired microarchitecture of bone tissue, leading to increased fragility and fractures. Methods: We screened 1855 postmenopausal female, aged from 50 to 80, the residents of Tashkent, Namangan and Qarshi, three cities with the largest populations in Uzbekistan. The duration of postmenopausal period was ≥1 year. Results: The study revealed unequal prevalence of OP with the least in Qarshi (27.3%) compared to Tashkent (33.5%) and Namangan (51.1%). Conclusions: Osteoporosis is common among women at age 50 and over, who live in the cities with largest population in Uzbekistan (Tashkent, Namangan and Qarshi). The risk factors in the studied cohort of women included decrease of body mass, irregular consumption of dairy products and irregular physical activity, history of fractures, and duration of menopause.