Metal Complexes of Gatifloxacin: Synthesis, Characterization and Evaluation of Biological Activity

Dave, Nikunj and Bhatt, Hardik (2021) Metal Complexes of Gatifloxacin: Synthesis, Characterization and Evaluation of Biological Activity. Asian Journal of Chemical Sciences, 10 (4). pp. 98-107. ISSN 2456-7795

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Official URL: https://doi.org/10.9734/ajocs/2021/v10i419109

Abstract

The antibiotic agent Gatifloxacin is well known for its drug design and coordinating ability towards metal ions. In this paper, synthesis and biological activity of Mn(II), Co(II), Ni(II), Cu(II) and Mg(II) complexes of gatifloxacin is reported. Ligand is itself prepared using o-phenylenediamine (OPD) and 3-acetyl coumarin. The structure of complexes has been investigated using some physiochemical and spectroscopic techniques. In vitro evaluation of these complexes was also carried out for antibacterial and antimicrobial activity. Some complexes exhibited promising anti-bacterial and antimicrobial activity compared to gatifloxacin drug.

Item Type:	Article
Subjects:	Eurolib Press > Chemical Science
Depositing User:	Managing Editor
Date Deposited:	03 Feb 2023 07:13
Last Modified:	15 Sep 2023 05:03
URI:	http://info.submit4journal.com/id/eprint/1213

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