Biochemical profile changes in stored donor blood for transfusion

AlMoshary, May and Al Mussaed, Eman and Arabdin, Maria (2019) Biochemical profile changes in stored donor blood for transfusion. Pakistan Journal of Medical Sciences, 35 (6). pp. 1697-1700. ISSN 1682-024X

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Abstract

Objectives: This study’s aim was to find out that how various biochemical parameters of donor blood are affected during storage.

Methods: This cross-sectional study was conducted in hematology Unit of Rehman Medical Institute, Peshawar and Fatimid Foundation, Peshawar Khyber Pakhtunkhwa, over a period of six months from June 2018 to November 2018. This study includes 300 healthy volunteer donors. Analysis of stored blood was done at 0, 3, 7, 14- and 21-days interval. Data were recorded and analyzed in SPSS v 20. A p value of less than 0.05 was taken as significant.

Results: Three hundred healthy volunteer donors were included in the study in which 63% were male and 37% were females. Mean age was 26.54±7.3 years with age range from 23-46 years. Out of 300 donors 15.33% were O+, 35.33%, 9.66% B+, 8.33% A+, 7.66% AB+, 7.66% O-, 7% A- and 9% B-. Significant. Changes were observed in serum potassium, LDH, pH, serum chloride, serum sodium and AST levels. (p:<0.001). however, storage did not affect rest of the parameters.

Conclusion: This study reveals that during storage certain changes occur in haematological and biochemical parameters which ultimately may put patients at risk.

Item Type: Article
Subjects: Eurolib Press > Medical Science
Depositing User: Managing Editor
Date Deposited: 25 Apr 2023 04:37
Last Modified: 20 Jan 2024 10:22
URI: http://info.submit4journal.com/id/eprint/1682

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