Zahidin, Muhamad Aidil and Mohd Noor, Noor Haslina and Johan, Muhammad Farid and Abdullah, Abu Dzarr and Zulkafli, Zefarina and Edinur, Hisham Atan (2021) A Review on Secondary Immune Thrombocytopenia in Malaysia. Healthcare, 10 (1). p. 38. ISSN 2227-9032
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Abstract
Immune thrombocytopenia (ITP) is an acquired autoimmune disease that occurs in adults and children. In Malaysia, the clinical practice guideline (CPG) for the management of ITP was issued in 2006, which focused almost exclusively on primary ITP (pITP), and only a few secondary ITP (sITP) forms were addressed. All published (twenty-three) sITP articles among children and adults in Malaysia, identified on the academic databases were retrieved. The articles were published between 1981 and 2019, at a rate of 0.62 publications per year. The publications were considered low and mainly focused on rare presentation and followed-up of secondary diseases. This review revealed that sITP in Malaysia is commonly associated with autoimmune diseases (Evan’s syndrome, SLE and WAS), malignancy (Kaposi’s sarcoma and breast cancer) and infection (dengue haemorrhagic fever, Helicobacter pylori and hepatitis C virus). The relationship between ITP and autoimmune diseases, malignancy and infections raise the question concerning the mechanism involved in these associations. Further studies should be conducted to bridge the current knowledge gap, and the further information is required to update the existing CPG of management of ITP in Malaysia.
Item Type: | Article |
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Uncontrolled Keywords: | secondary immune thrombocytopenia; autoimmune disease; malignancy; infection; clinical practice guideline |
Subjects: | Eurolib Press > Medical Science |
Depositing User: | Managing Editor |
Date Deposited: | 09 Sep 2023 09:33 |
Last Modified: | 09 Sep 2023 09:33 |
URI: | http://info.submit4journal.com/id/eprint/2306 |