Bielecka, B. and Gorczyca, I. and Jelonek, O. and Wożakowska-Kapłon, B. and Severino, Paolo (2021) Trends in Stroke Prevention between 2014 and 2018 in Hospitalized Atrial Fibrillation Patients. Cardiology Research and Practice, 2021. pp. 1-8. ISSN 2090-8016
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Abstract
In recent years, significant changes in stroke prophylaxis in patients with atrial fibrillation (AF) have been observed. Non-vitamin K antagonist oral anticoagulants (NOACs) are more commonly used in the prevention of thromboembolic complications in patients with AF. The aim of the study was to evaluate recommended stroke prophylaxis in patients with AF and to identify predictors of using NOACs in patients treated with anticoagulant therapy. The present study was a retrospective, observational, single-center study which included consecutively hospitalized patients in the reference cardiology center from January 2014 to December 2018. In the study group of 4027 patients with AF, to prevent thromboembolic complications, OACs were used in 3680 patients (91.4%), an antiplatelet drug(s) was used in 124 patients (3.1%), and 223 patients (5.5%) did not undergo any thromboembolic event prevention. In the group of 3680 patients treated with OACs, 2311 patients (62.8%) received NOACs and 1639 patients (37.2%), VKAs. Independent predictors of the use of NOACs were age (OR, 1.02; 95% CI, 1.01–1.03; ), a previous thromboembolic event (OR, 1.29; 95% CI, 1.01–1.65; ), nonpermanent AF (OR, 1.61; 95% CI, 1.34–1.93; ), and eGFR (OR, 1.22; 95% CI, 1.02–1.46; ). Between 2014 and 2018, an increase of patients treated with OACs, mainly with NOACs, was observed. Age, past thromboembolic complications, nonpermanent AF, and preserved renal function determined the choice of NOACs.
Item Type: | Article |
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Subjects: | Eurolib Press > Medical Science |
Depositing User: | Managing Editor |
Date Deposited: | 29 Nov 2022 05:05 |
Last Modified: | 26 Feb 2024 04:13 |
URI: | http://info.submit4journal.com/id/eprint/476 |