An Unusual Association of Hyper-IgE Syndrome with Celiac Disease: A Case Report

Agadr, Aomar and Hassani, Amal and Abilkassem, Rachid and Ourrai, Abdelhakim and Radi, Abdelilah and Mahi, Jihane El and Hachim, Ghita (2022) An Unusual Association of Hyper-IgE Syndrome with Celiac Disease: A Case Report. Journal of Advances in Medical and Pharmaceutical Sciences, 24 (9). pp. 8-13. ISSN 2394-1111

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Abstract

Hyper-IgE syndrome (HIES) is a primary immunodeficiency disorder characterized by eczema, cold abscesses, pneumonia, eosinophilia, and a very high serum IgE concentration. An association with celiac disease is rare. Immunodeficiency and autoimmunity are two manifestations of immune system dysfunction that can be associated with common pathophysiological links. We present the case of a 3-year-old child with psychomotor retardation and a history of recurrent infections who had generalized eczema, failure to thrive, and abdominal distension with hepatosplenomegaly. The patient improved after receiving a monthly intravenous immunoglobulin infusion and a gluten-free diet.

Item Type: Article
Uncontrolled Keywords: HyperIgE syndrome; celiac disease; immune deficiency; infection
Subjects: Eurolib Press > Medical Science
Depositing User: Managing Editor
Date Deposited: 04 Nov 2022 04:36
Last Modified: 30 Dec 2023 13:20
URI: http://info.submit4journal.com/id/eprint/50

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